Dr. Jerome GoldsteinMeet Dr. Jerome Goldstein of the San Francisco Clinical Research Center

Jerome Goldstein, M.D. is a Board-certified medical neurologist who has a special interest in the diagnosis, treatment, prevention, and cure of headache. He has been directing the San Francisco Clinical Research Center for more than forty years.

A graduate from the SUNY Upstate Medical Center in Syracuse, New York, Dr. Goldstein completed his Neurology residency at the University of California in San Francisco in 1970.

Dr. Goldstein has directed research studies on every new 5-HT 1D receptor agonists, including the original pilot studies done on Imitrex® in the United States. He also has conducted clinical trials on all new prophylactic agents in headache.

Industry Consultant in Data Safety Monitoring Boards

In addition to the directing the San Francisco Clinical Research Center, Dr. Goldstein is a leading industry consultant in data safety monitoring boards. He is part of an independent group of experts who monitor patient safety and treatment data while a clinical trial is ongoing. As part of a group, which remains independent from the company sponsoring the trials, Dr. Goldstein and his group convene at predetermined intervals (three to six months typically) and review unblinded results.

A noted researcher, Dr. Goldstein has authored numerous publications in the field of headaches. In addition to his writing, he is a leader in multimedia scientific and education presentations on pain and headaches. He has presented for the International Headache Society in Barcelona, Spain, the Brazilian Headache Society in Brazil, the German Pain Congress in Dusseldorf, Germany, the European Federation of Neurological Societies in Seville, Spain, the XII Migraine International Symposium in London, England, and the 4th Congress of European Headache Federation in Corfu, Greece. These presentations have covered the following topics: the comparison of the 5-HT 1D receptor agonists, the role of opiates in pain and headache management, caffeine in headache medications and new triptans.


  • Director of San Francisco Clinical Research Center
  • Director of San Francisco Alzheimer’s and Dementia Clinic
  • Director of San Francisco Headache Clinic
  • Past President of the Headache and Facial Pain Section of the American Academy of Neurology
  • Assistant Clinical Professor of Neurology at the University of California in San Francisco
  • Fellow member of the American Association for the Study of Headache


  • American Board of Psychiatry and Neurology

Association Memberships:

  • The American Headache Society
  • The International Headache Society
  • The National Headache Foundation
  • The American Academy of Neurology’s Section’s Committee for Practice Standards and Director of its Annual Course, “Case Studies in Headache”

Find Out More Information

Dr. Jerome Goldstein is the Director of The San Francisco Clinical Research Center, which is conveniently located at 909 Hyde St., Suite #322 in San Francisco. The office can be reached at (415) 673-4600. We will make every effort possible to evaluate you for our clinical research programs and try our best to evaluate you for eligibility to access our free research programs. Our reception team will answer every call during business hours and return all after hours calls the next business day. We will also make every effort to schedule an appointment with us within 1-2 weeks or sooner.

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